Posts Tagged ‘Clostridium Botulinum’

What is Botox®, and How Does it Work?

Tuesday, September 22nd, 2009
Patricia Woloch recently asked:


Since its introduction and approval in 2002, Botox® has become the number one cosmetic surgery procedure in the United States, according to the statistics of the American Society of Plastic Surgeons. This seemingly magic cure for deep-set frown lines and rugged furrowed brows is very popular among politicians and Hollywood actors. With its relatively low cost and long lasting effects, over 4 million people in the U.S chose Botox treatments in 2006 alone.

Botox is made of a sterile form of botulinum toxin, which is injected under the skin to deaden the nerve endings that cause wrinkles. When injected, the toxin inhibits the release of the chemical acetylcholine, which signals the muscles in your face to contract. Since those muscles are chemically paralyzed, they do not pinch the skin and cause wrinkles to form.

Even though Botox is made from a deadly toxin produced by Clostridium botulinum, it is relatively safe. The toxin itself is extracted from the live bacteria, and no live bacteria are injected into the skin. There is no chance of contracting botulism. Only small, localized doses of the toxin are administered during treatments, and the risks are relatively small.

The toxin treatment was first approved to treat blepharospasm (twitching eye muscles) in 1989. Cosmetically desirable effects of Botox were noticed when the frown lines between the eyebrows were observed to soften following treatment applied for eye muscle disorders. Subjects no longer had deep creases or folds of tissue near the areas where the injections were given.

These observations lead to clinical trials and subsequent FDA approval as a cosmetic application in April 2002. As of 2006, Botox injection are the most common cosmetic procedure in the United States.

Since Botox is not an injectable filler, but a chemical blocker, many wrinkle lines are not treated with Botox. Sun damaged skin and other wrinkles that are not caused by neuromuscular action are better treated with injectable fillers like collagen or Restylane.

The number of injections needed is based on the area being treated. Crow’s feet might only take from two to five injections where as glabellar lines (furrowed brow) might take eight to ten injections. The injection sessions usually only take from ten to fifteen minutes of your time, and you can resume normal activities right away.

Like all medical treatment, Botox does have potential side effects.

Some of the side effects may include:

• Pain

• Bruising

• Redness

• Nausea

• Headache

• Ptosis (drooping of upper eyelid)

There is virtually no down time after a Botox injection treatment, you can resume a normal day as soon as you leave the physician’s office. Be careful not to rub or massage the treated area as this could cause the injected material to migrate to other areas. Full results are seen after a few days, and last up to six months. Re-injections are needed to maintain your new fresh appearance. Cosmetic Botox® injections should be given no more than once every three months.

It is important to find a doctor who has experience with Botox injections to minimize risks, and ensure proper dosing. Botox is delivered to the physician in dry form and must be reconstituted with the right amount of saline. Each vial of Botox is intended for onetime use on a single patient.

A growing phenomenon around the country is the so-called “Botox parties” where a clinician will open up his clinic and basically throw a party. As the participants wait their turn for injection, they socialize and have fun. The FDA has issued warnings about these types of events as they can diminish the serious nature of the injections and their use. However, when compared to other cosmetic treatments, the complication rate of Botox is remarkably low. A recent campaign to put more severe warnings on Botox by the group Public Citizen, listed only one death from cosmetic treatment with the drug. Considering the millions of treatments performed annually, this represents a fraction of a tenth of a percent of a percent of risk.





Botox for Migraines

Thursday, August 27th, 2009
Sandra Kim Leong recently asked:


Botox (botulinum toxin) is a neurotoxin injection. Neurotoxins are the toxin that attacks the nerve cells. Botox is the sterile and vacuum-dried form of the botulinum toxin type A. It is usually produced from the Hall strain of Clostridium botulinum. Botox can be used in conditions where the hyperactivity of muscles causes the health and medical related problems.

Botox for migraines helps to weaken or paralyze the hyper activated muscles by suppressing the release of acetylcholine, which mainly causes the transmission of nerve impulses at synapses and myoneural. This treatment can also be used for reducing the pain associated with the cervical dystonia, achalasia and rectal fissures. Botox is usually injected directly into the affected muscles.

There are different theories to explain the working of the Botox for the elimination of migraine headaches. According to one theory, as tension and spasms are the main causes of migraines, Botox eliminate the headaches by eliminating the muscle tension. It is also believed that Botox reduces the headaches by inhibiting the transmission of nerve cells. According to this theory headache is caused due to the increased amount of signals send by the nerves.

Since Botox for migraines take several weeks to take effect after the injection, it is better to not inject more than once every three months. The pain in the injected area remains for a couple of days after injecting the Botox. This can be pointed out as the main drawback of this neurotoxin. More studies are still performing on this neurotoxin.

You will need to consult their physician before taking the botulinum toxin type. Especially, the pregnant women and women who could become pregnant during the treatment must take advice from their physician. Botulinum toxin type A for migraines should never be used with any other botulinum toxin or any other medication that affect the nerves or muscles.

One of the main limitations for the use of Botox for migraines is the cost of treatment. The Botox injections are usually not covered by any insurance and the cost of Botox treatment can be around $350 for each targeted area. Hence this treatment is very expensive compared to the other migraines treatments such as the prescription drug lmitrex and nasal sprays. But the drugs like lmitrex and nasal sprays are only used as a preventative drug and are not designed to prevent all the migraine attack for up to four or more months like Botox.

Using Botox for migraines should be considered very carefully. It is still early days yet before one truly knows what all the side effects can be. There is considerable chance for occurring side effects during the Botox treatment period. Hence you are advised of the possibility of needing to take emergency medical attention if you experience any serious side effects such as an allergic reaction, difficulty in breathing, talking or swallowing, chest pain, irregular heartbeats or excessive muscl





Botox: A Hit In The Cosmetic World

Tuesday, August 11th, 2009
Robert Thatcher recently asked:


Who would have thought that something that is supposedly poisonous could have so many people clamoring for it?

Skepticism proven wrong

When botox hit the market, many were skeptical on the effects of these newly developed chemical. A protein complex made from a bacterium called clostridium botulinum, many feared that the chemical will have the same effect on the skin as it has on the body. For those who do not yet know, botox come from the same toxin that can cause food poisoning in humans.

It turned out to be quite effective and a huge huge success especially in the cosmetic surgery business. It is also being used to relieve pain in muscle areas of people who have has chronic pains. Its is actually so effective that people who were normally confined to their homes because of the pain now live normal lives.

Popular alternative

Since botox inhibits the release of acetylcholine, a chemical responsible for the contraction of muscles in various parts of the body, it is primarily used to clear out wrinkles and frown lines in the face through injection in the areas of concern. The effect of the drug can last for several months. Only small amounts of the toxin are however used for these cosmetic procedures. Too much use of the toxin can produce disastrous side effects.

In 2001 alone, almost 1.6 million Americans have had botox injections in different areas of their bodies. This is a significant increase from 2000’s figures. In fact, botox injections are even more popular than the immensely popular ****** enhancement and ****** augmentation procedures.

Botox parties

The procedure has become so popular in fact that people even organize parties and social events just for the occasion of injecting botox. This is actually part of the marketing campaign that has gained botox injections so many followers. Women (and men) who regularly inject botox for maintenance get together in small gatherings and simultaneously inject botox. Outsiders especially those who have not yet tried the drugs but are interested can join the party.

Abuse and overuse

One of the growing concerns in the industry is the potential abuse of the drug. Although botox is basically a prescription drugs, there are unqualified people who are distributing the medicine. And because the drug must be injected again and again to maintain its effect, there is also the danger of the drug being overused or for people to over-apply thinking that it will lengthen the effect of the drug.

Injecting too much botox or accidentally injecting it on the wrong area can cause droopy eyelid muscles, a condition called ptosis. This could last for several weeks. Other side effects that botox have are headaches, respiratory infections, flu-like symptoms and even nausea. Some people will also experience pain on the area where the botox was applied as well as redness and swelling. There will also some muscle weakness around the area where the botox was applied.

Contraindications

Although botox is available to all people, there are some who are allergic to the toxin. So it is best that one consults a physician first before applying the drug. Although there has never been any studies or research on the effect of botox on pregnant women and on nursing women, medical people err on the safe side and just prohibit the drug.





A Brief Introduction To Botox

Saturday, July 25th, 2009
Kadence Buchanan recently asked:


You hear about Botox everywhere these days. A relatively simple procedure can lead to a clearing of wrinkles and, consequently, a more youthful appearance. The Botox procedure was approved by the United States Food and Drug Administration in April of 2002. Botox is the trade name for Botulism Toxin A, which is actually a form of food poisoning! There are several different Botulism toxins, ranging from Botulism Toxin A to Botulism Toxin G. Botulism is caused by the ingestion of the bacteria that is known as clostridium botulinum. Botulism is actually a neurotoxin that is released by the bacteria once ingested. The side effects that are caused by ingesting this neurotoxin can be as serious as paralysis! People have died in the past from botulism due to the fact that the neurotoxin can cause the respiratory muscles to shut down, causing an inability to breathe. In short, the neurotoxin attacks the body by attaching itself to nerve endings, causing them to not be able to release acetylcholine, a neurotransmitter that is responsible for contracting muscles.

Botulism injections are performed to effectively paralyze the muscles of the face, stopping them from moving and consequently causing a lack of wrinkling due to muscle movement. After Botox is injected, it can take anywhere from a few hours to a few days to freeze the muscles. The effects are not permanent, and a Botox treatment can last anywhere from three months to eight months. People that use Botox for beauty often arrange gatherings in which several adults perform the procedure, with such catchy themes as “Botox and Bagels”. A Botox injection usually costs somewhere between 250 and 500 dollars per shot. Botox injections are generally well tolerated, but they should not be performed on anyone who is pregnant, nursing, or on an antibiotic regimen. If you are thinking of getting a Botox injection, check with your doctor to ensure that the procedure will go properly for you. Botox may interfere with medications that you may be taking, so it’s generally best to speak to a doctor before getting an injection.

In addition to aiding those who wish to clear their face of wrinkles, Botox has been used to help several medical conditions. When Botox was first used clinically, it was employed to treat neurological disorders. Writer’s cramp can be alleviated by a Botox injection, and ****** spasms and spasmodic dyphodia have been under consideration for Botox treatment.





Botox: Anti Wrinkle Injections May Not Be All They’re Cracked Up To Be

Thursday, May 28th, 2009
Dylan recently asked:


Beautyblogtalk.com’s expansive collection of reviews features even more facts on Botox.

Find a detailed review of Botox at Beautifulreview.com, a highly informative skin care product review site.







Review Summary

Botox™ is safe to use with other topically applied beauty products such as creams sold over the counter. Botox™, however, is available only through a qualified physician. The makers of this product have compiled a network of recommended physicians available to provide services through the manufacturer’s website. Millions of men and women have received the Botox™ treatment and report a high level of success.

Ingredients at a Glance

Botox™ uses only one ingredient, a purified protein known as Clostridium botulinum bacterium.

Ingredients in Focus

This sole ingredient in the Botox™ allows the signs of aging to disappear for up to 4 months by minimizing the movement of certain muscles in the face. According to the maker of the product users still have a full range of motion to make normal ****** expressions, although sometimes use of the product is quite evident. Instead, it limits the movement of muscles responsible for making the face look wrinkled. The manufacturer claims that the product works quickly so one doesn’t have to wait months to see results. The results may appear as quickly as in a few days. The product has treated millions of patients and resulted in few complaints compared to the many success stories.

Positives

Botox™ has a high rate of success. This product is safely administered by a medical doctor.



Negatives

Botox™ has no guarantees. Botox™ avoids using or promoting products with ingredients such as Matrixyl 3000. This product is temporary regardless of how many treatments one receives over time. Botox™ may require paying a physician out of pocket, since it’s not a medical expense per se.



Final Thoughts


Botox™ works very well for many patients. It requires a simple procedure which includes injection into the ****** region. Some may feel discomfort or be afraid of needles, but at this time there are no alternative means of treatment. The manufacturer doesn’t list the price of the product since it’s administered through independent physicians the price may vary, but you may expect it to be pricey. There do not appear to be any common side effects. Since the product is administered by a physician it provides an opportunity for one to inquire about any concerns prior to treatment.



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