Posts Tagged ‘Fda Approval’

Botox is Probably the Most Talked About and Popular Cosmetic Procedure of Today

Wednesday, January 27th, 2010
Freelance Writer recently asked:


Botox

Botox is probably the most talked about and popular cosmetic procedure of today. Since its release millions of women, and men have been rushing into the offices of the nearest practitioners to have the procedure done. With the FDA approval for cosmetic procedure came the emergence of the trendy “Botox parties.” Practitioners began sending out invitations to potential candidates for food, drinks, conversation and a Botox injection. While the procedure itself is quick, and virtually painless you would be well advised to discuss the procedure with your doctor beforehand and schedule an appointment to have the treatment administered in a clinical setting, rather than at a social affair.

Botox is a trade name for the neurotoxin botulinum type A; a complex protein produced by the bacterium Clostridium botulinum. The botulinum toxin acts as a nerve blocker and binds itself to the nerves leading to the muscle preventing the release of acetylcholine, a neurotransmitter that stimulates the muscle to contract. Botulism is a paralyzing form of food poisoning that occurs when the neurotoxin is ingested, the reason that it can be fatal is usually due to the paralysis of the respiratory muscles making it impossible to breath. So in this way, Botox is related to the food borne illness, but that is where the similarities end. With controlled application the botulinum type A can be injected into specific muscles and alleviate many problems associated with muscle spasms, or involuntary contraction of the muscle. Botox Cosmetic, when injected into the corrugator and procerus muscles, temporarily prevents them from contracting and this is what reduces the appearance of glabellar, or frown lines. Basically if the muscles cannot contract, or scrunch up, the wrinkles go away.

Botox has been indicated in treatment of several medical conditions, and has been proven to successfully treat blepharospasm, a condition which causes the involuntary spasmodic contraction of certain eye muscles, strabismus, a manifest lack of parallelism of the visual axes of the eyes, or crossed eyes and cervical dystonia, a state of abnormal tension in any of the tissues resulting in the impairment of a person’s voluntary movement in the neck area. It has also been used to treat other dystonias, such as writer’s cramp, as well as facial spasms, head and neck tremors and hyperhidrosis, or excessive sweating. Other applications for which Botox may be useful are currently being investigated. By injecting the toxin into the affected muscles the spasms or contractions that normally occur are greatly reduced or eliminated. The effects of the treatment for these conditions can be seen and felt anywhere from a couple of hours to a couple of days after treatment, they are temporary and will last anywhere from three to eight months.

Botox Cosmetic is a simple non-surgical treatment that has been proven to treat moderate to severe glabellar, or frown lines and eliminates wrinkles temporarily. It is the only treatment of its kind approved by the FDA for use in adult patients aged 18-65. The FDA approved the use of Botox for cosmetic use in April of 2002 and before that it was approved for use to treat certain medical conditions since 1989. In the year 2005 there were over 3 million procedures performed.

The procedure itself takes about ten minutes and involves a few tiny injections. The injections go directly into the muscle and then it enters into the nerve endings to block the chemical that causes the muscle to contract. Once the muscles are at rest and can no longer contract the appearance of the skin becomes firmer and smoother and the lines or wrinkles that would normally be see are greatly diminished or eliminated altogether. The results of the treatment can usually be seen within hours and will last for about four months. Because the treatment targets only certain areas and only the muscles that are affected the risk of the toxin spreading is severely reduced.

A topical anesthetic is usually applied to the area that will be treated to numb the injection site. There is usually only minimal pain or discomfort associated with the actual injection but it does not persist past the process of injection. There is usually no downtime resulting from the procedure so return to work and normal activity can usually resume immediately. There is usually little to no bruising, bleeding, swelling, pain or other discomfort involved with the procedure.

It would seem only natural to think that there would be a lot of risk involved with injecting toxins into the body but in fact Botox injections are believed to be safe and result in few side effects. Any side effects that may arise from the treatments typically last no more than six months since the treatment itself is temporary. The most common, but rare side effects associated with treatment include bruising at the site of the injection, headache, respiratory infection, nausea, and flu like symptoms. In rare occurrences the Botox cosmetic may spread to adjoining muscles and cause temporary paralysis. In less than 1% of patients this can cause drooping of the eyelid. Less frequently occurring side effects include pain in the face, erythema, or abnormal redness at the injection site, and muscle weakness. These adverse reactions occurred in less than 3% of patients and occurred within the first week of treatment. They are thought to be associated with the injection itself.

There are only few restrictions to who is eligible to receive treatment. Those who are pregnant or nursing are definitely ineligible. Those who suffer from neuromuscular disease have allergies to certain medications or who are taking certain medications should discuss this in depth with their physician, as they may not be eligible for treatment. Any medications that are being taken should always be disclosed as certain medications; mostly antibiotics can alter the effects of Botox. Many people return for new treatments as soon as the effects start to wear off. The cost of the procedure varies depending on how many areas are being treated and who is performing the procedure. The price typically ranges from $175 for one area of treatment to $800 for three or more areas of treatment.





Botox is Probably the Most Talked About and Popular Cosmetic Procedure of Today

Saturday, December 5th, 2009
Freelance Writer recently asked:


Botox

Botox is probably the most talked about and popular cosmetic procedure of today. Since its release millions of women, and men have been rushing into the offices of the nearest practitioners to have the procedure done. With the FDA approval for cosmetic procedure came the emergence of the trendy “Botox parties.” Practitioners began sending out invitations to potential candidates for food, drinks, conversation and a Botox injection. While the procedure itself is quick, and virtually painless you would be well advised to discuss the procedure with your doctor beforehand and schedule an appointment to have the treatment administered in a clinical setting, rather than at a social affair.

Botox is a trade name for the neurotoxin botulinum type A; a complex protein produced by the bacterium Clostridium botulinum. The botulinum toxin acts as a nerve blocker and binds itself to the nerves leading to the muscle preventing the release of acetylcholine, a neurotransmitter that stimulates the muscle to contract. Botulism is a paralyzing form of food poisoning that occurs when the neurotoxin is ingested, the reason that it can be fatal is usually due to the paralysis of the respiratory muscles making it impossible to breath. So in this way, Botox is related to the food borne illness, but that is where the similarities end. With controlled application the botulinum type A can be injected into specific muscles and alleviate many problems associated with muscle spasms, or involuntary contraction of the muscle. Botox Cosmetic, when injected into the corrugator and procerus muscles, temporarily prevents them from contracting and this is what reduces the appearance of glabellar, or frown lines. Basically if the muscles cannot contract, or scrunch up, the wrinkles go away.

Botox has been indicated in treatment of several medical conditions, and has been proven to successfully treat blepharospasm, a condition which causes the involuntary spasmodic contraction of certain eye muscles, strabismus, a manifest lack of parallelism of the visual axes of the eyes, or crossed eyes and cervical dystonia, a state of abnormal tension in any of the tissues resulting in the impairment of a person’s voluntary movement in the neck area. It has also been used to treat other dystonias, such as writer’s cramp, as well as ****** spasms, head and neck tremors and hyperhidrosis, or excessive sweating. Other applications for which Botox may be useful are currently being investigated. By injecting the toxin into the affected muscles the spasms or contractions that normally occur are greatly reduced or eliminated. The effects of the treatment for these conditions can be seen and felt anywhere from a couple of hours to a couple of days after treatment, they are temporary and will last anywhere from three to eight months.

Botox Cosmetic is a simple non-surgical treatment that has been proven to treat moderate to severe glabellar, or frown lines and eliminates wrinkles temporarily. It is the only treatment of its kind approved by the FDA for use in adult patients aged 18-65. The FDA approved the use of Botox for cosmetic use in April of 2002 and before that it was approved for use to treat certain medical conditions since 1989. In the year 2005 there were over 3 million procedures performed.

The procedure itself takes about ten minutes and involves a few tiny injections. The injections go directly into the muscle and then it enters into the nerve endings to block the chemical that causes the muscle to contract. Once the muscles are at rest and can no longer contract the appearance of the skin becomes firmer and smoother and the lines or wrinkles that would normally be see are greatly diminished or eliminated altogether. The results of the treatment can usually be seen within hours and will last for about four months. Because the treatment targets only certain areas and only the muscles that are affected the risk of the toxin spreading is severely reduced.

A topical anesthetic is usually applied to the area that will be treated to numb the injection site. There is usually only minimal pain or discomfort associated with the actual injection but it does not persist past the process of injection. There is usually no downtime resulting from the procedure so return to work and normal activity can usually resume immediately. There is usually little to no bruising, bleeding, swelling, pain or other discomfort involved with the procedure.

It would seem only natural to think that there would be a lot of risk involved with injecting toxins into the body but in fact Botox injections are believed to be safe and result in few side effects. Any side effects that may arise from the treatments typically last no more than six months since the treatment itself is temporary. The most common, but rare side effects associated with treatment include bruising at the site of the injection, headache, respiratory infection, nausea, and flu like symptoms. In rare occurrences the Botox cosmetic may spread to adjoining muscles and cause temporary paralysis. In less than 1% of patients this can cause drooping of the eyelid. Less frequently occurring side effects include pain in the face, erythema, or abnormal redness at the injection site, and muscle weakness. These adverse reactions occurred in less than 3% of patients and occurred within the first week of treatment. They are thought to be associated with the injection itself.

There are only few restrictions to who is eligible to receive treatment. Those who are pregnant or nursing are definitely ineligible. Those who suffer from neuromuscular disease have allergies to certain medications or who are taking certain medications should discuss this in depth with their physician, as they may not be eligible for treatment. Any medications that are being taken should always be disclosed as certain medications; mostly antibiotics can alter the effects of Botox. Many people return for new treatments as soon as the effects start to wear off. The cost of the procedure varies depending on how many areas are being treated and who is performing the procedure. The price typically ranges from $175 for one area of treatment to $800 for three or more areas of treatment.





Is Botox Right For You?

Tuesday, August 11th, 2009
Heather Colman recently asked:


Botulin toxin, sold commercially under the brand name Botox, is an exceptionally potent neurotoxin that has found a variety of remarkable uses in modern medicine. It is also the most popular nonsurgical medical cosmetic treatment in the UK and USA.

Researchers discovered in the 1950s that injecting overactive muscles with minute quantities of botulinum toxin type A decreased muscle activity by blocking the release of acetylcholine at the neuromuscular junction, thereby rendering the muscle unable to contract for a period of 4 to 6 months.

Alan Scott, a San Francisco ophthalmologist, first applied tiny doses of the toxin in a medicinal sense to treat crossed eyes and uncontrollable blinking, but a partner was needed to gain regulatory approval to market his discovery as a drug. Allergan, Inc., a small pharmaceutical company that focused on prescription eye therapies and contact lens products, bought the rights to the drug in 1988 and quickly received FDA approval in 1989. Allergan renamed the drug Botox.

Cosmetic benefits of Botox were quickly realized when the frown lines between the eyebrows appeared to soften following treatment for eye muscle disorders. The increased potential of Botox as a cosmetic treatment led to clinical trials and subsequent FDA approval in April 2002.

Currently, Botox is finding enormous additional potential in several therapeutic areas including the treatment of migraine headaches, cervical dystonia (a neuromuscular disorder involving the head and neck), blepharospasm (involuntary contraction of the eye muscles), and severe primary axillary hyperhidrosis (excessive sweating). Other uses of botulinum toxin type A that are widely known but not approved by FDA include urinary incontinence, **** fissure, spastic disorders associated with injury or disease of the central nervous system including trauma, stroke, multiple sclerosis, or cerebral palsy and focal dystonias affecting the limbs, face, jaw, or vocal cords. It is also used off label for the treatment of TMJ, but a side effect in some patients is a jaw left too weak to chew solid food for about 3 months after the injection.

Treatment and prevention of chronic headache and chronic musculoskeletal pain are emerging uses for botulinum toxin type A. In addition, there is evidence that Botox may aid in weight loss by increasing the gastric emptying time.

As an alternative to Botox, anti-aging creams are heavily marketed and advertised on television, with the promise of looking younger and the reduction in visible wrinkles on the skin.

Traditionally, they have been targeted towards women, but products specifically targeting men are now common. This change may be due to the fact that many societies in recent years have seen an increased focus on young looks, including in men. Some men report that looking younger makes it easier to get a good job.

There are a range of cosmetic ‘treatments’ for the appearance of wrinkles on the skin such as plastic surgery and botox injections. One of the marketed advantages of anti-aging cream is that it is an alternative to these more extreme cosmetic treatments.

Critics take the view that the manufacturers of these products prey on the fears of women, and that the advertisements abuse science by claiming that their products are scientifically proven to work. It is said that the ’scientific data’ is based on the perception of women who have tried the product, and are asked whether or not they think they look younger. These are the hallmarks of a placebo.

However, it is plausible that some of the anti-aging products could have a rejuvenating effect, as promised. However, the effects of most anti-aging products likely depends on their concentration and mode of application, making their effects less certain.

Permission is granted to reprint this article as long as no changes are made, and the entire resource box is included.






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